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16-day Main river cruise

Danube

Looking for 16-day Main river cruise vacation? Discover best 16-day cruise vacations on Main river. 16-day Main river cruising allows you to both enjoy the ever-changing scenery and also discover the unique customs, cultures and cuisines. Enjoy beautiful sceneries, spectacular hills along the amazing Main river on your 16-day cruise vacation.


Find and plan your next 16-day Main river cruise

Uniworld Dutch-Belgian 16-day route

Uniworld, 16-day Dutch-Belgian from Budapest, June 3, 2022

Cruise Line: Uniworld; Cruise Ship: River Duchess; Duration: 16-day;

Ports of Call: Budapest, Budapest, Vienna, Vienna, Wachau Valley, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim, Frankfurt, Rudesheim, Cologne, Amsterdam, Amsterdam;

Uniworld Main 16-day route

Uniworld, 16-day Main from Amsterdam, June 18, 2022

Cruise Line: Uniworld; Cruise Ship: River Duchess; Duration: 16-day;

Ports of Call: Amsterdam, Amsterdam, Cologne, Rudesheim, Frankfurt, Wertheim, Wurzburg, Main River, Bamberg, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest, Budapest, Budapest;

Avalon Rhine 16-day route

Avalon, 16-day Rhine from Basel, June 22, 2022

Cruise Line: Avalon; Cruise Ship: Tranquility II; Duration: 16-day;

Ports of Call: Basel, Breisach, Strasbourg, Rhine Gorge, Frankfurt, Main River, Wurzburg, Bamberg, Nuremberg, Roth, Regensburg, Linz, Wachau Valley, Vienna, Budapest, Budapest;

Avalon Danube 16-day route

Avalon, 16-day Danube from Budapest, July 17, 2022

Cruise Line: Avalon; Cruise Ship: Tranquility II; Duration: 16-day;

Ports of Call: Budapest, Vienna, Vienna, Wachau Valley, Passau, Regensburg, Roth, Nuremberg, Bamberg, Wurzburg, Main River, Frankfurt, Rhine Gorge, Strasbourg, Breisach, Basel;

Uniworld Dutch-Belgian 16-day route

Uniworld, 16-day Dutch-Belgian from Budapest, July 17, 2022

Cruise Line: Uniworld; Cruise Ship: River Duchess; Duration: 16-day;

Ports of Call: Budapest, Budapest, Vienna, Vienna, Wachau Valley, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim, Frankfurt, Rudesheim, Cologne, Amsterdam, Amsterdam;

Uniworld Main 16-day route

Uniworld, 16-day Main from Amsterdam, August 1, 2022

Cruise Line: Uniworld; Cruise Ship: River Duchess; Duration: 16-day;

Ports of Call: Amsterdam, Amsterdam, Cologne, Rudesheim, Frankfurt, Wertheim, Wurzburg, Main River, Bamberg, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest, Budapest, Budapest;

Uniworld Dutch-Belgian 16-day route

Uniworld, 16-day Dutch-Belgian from Budapest, August 30, 2022

Cruise Line: Uniworld; Cruise Ship: River Duchess; Duration: 16-day;

Ports of Call: Budapest, Budapest, Vienna, Vienna, Wachau Valley, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim, Frankfurt, Rudesheim, Cologne, Amsterdam, Amsterdam;

Avalon Main 16-day route

Avalon, 16-day Main from Budapest, September 12, 2022

Cruise Line: Avalon; Cruise Ship: Tranquility II; Duration: 16-day;

Ports of Call: Budapest, Vienna, Vienna, Wachau Valley, Passau, Regensburg, Roth, Nuremberg, Bamberg, Wurzburg, Main River, Frankfurt, Rhine Gorge, Strasbourg, Breisach, Basel;

Uniworld Main 16-day route

Uniworld, 16-day Main from Amsterdam, September 14, 2022

Cruise Line: Uniworld; Cruise Ship: River Duchess; Duration: 16-day;

Ports of Call: Amsterdam, Amsterdam, Cologne, Rudesheim, Frankfurt, Wertheim, Wurzburg, Main River, Bamberg, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest, Budapest, Budapest;

Avalon Rhine 16-day route

Avalon, 16-day Rhine from Basel, September 27, 2022

Cruise Line: Avalon; Cruise Ship: Tranquility II; Duration: 16-day;

Ports of Call: Basel, Breisach, Strasbourg, Rhine Gorge, Frankfurt, Main River, Wurzburg, Bamberg, Nuremberg, Roth, Regensburg, Linz, Wachau Valley, Vienna, Budapest, Budapest;

Avalon Danube 16-day route

Avalon, 16-day Danube from Vienna, November 29, 2022

Cruise Line: Avalon; Cruise Ship: Tranquility II; Duration: 16-day;

Ports of Call: Vienna, Vienna, Wachau Valley, Passau, Regensburg, Nuremberg, Nuremberg, Nuremberg, Bamberg, Wurzburg, Main River, Frankfurt, Heidelberg, Strasbourg, Breisach, Basel;

Avalon Danube 16-day route

Avalon, 16-day Danube from Vienna, December 4, 2022

Cruise Line: Avalon; Cruise Ship: Impression; Duration: 16-day;

Ports of Call: Vienna, Vienna, Wachau Valley, Passau, Regensburg, Nuremberg, Nuremberg, Nuremberg, Bamberg, Wurzburg, Main River, Frankfurt, Heidelberg, Strasbourg, Breisach, Basel;

Uniworld Main 16-day route

Uniworld, 16-day Main from Amsterdam, May 4, 2023

Cruise Line: Uniworld; Cruise Ship: River Duchess; Duration: 16-day;

Ports of Call: Amsterdam, Amsterdam, Cologne, Rudesheim, Frankfurt, Wertheim, Wurzburg, Main River, Bamberg, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest, Budapest, Budapest;